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Wednesday, July 31, 2019

69. Stay Alert to Parkinson's Disease Now

Parkinson's Disease
Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms generally come on slowly over time. Early in the disease, the most obvious are shaking, rigidity, slowness of movement, and difficulty with walking. Thinking and behavioral problems may also occur. Dementia becomes common in the advanced stages of the disease. Depression and anxiety are also common, occurring in more than a third of people with PD. Other symptoms include sensory, sleep, and emotional problems. The main motor symptoms are collectively called "parkinsonism", or a "parkinsonian syndrome".
The cause of Parkinson's disease is generally unknown, but believed to involve both genetic and environmental factors. Those with a family member affected are more likely to get the disease themselves. There is also an increased risk in people exposed to certain pesticides and among those who have had prior head injuries, while there is a reduced risk in tobacco smokers and those who drink coffee or tea. The motor symptoms of the disease result from the death of cells in the substantia nigra, a region of the midbrain. This results in not enough dopamine in these areas. The reason for this cell death is poorly understood, but involves the build-up of proteins into Lewy bodies in the neurons. Diagnosis of typical cases is mainly based on symptoms, with tests such as neuroimaging being used to rule out other diseases.

There is no cure for Parkinson's disease, with treatment directed at improving symptoms. Initial treatment is typically with the antiparkinson medication levodopa (L-DOPA), with dopamine agonists being used once levodopa becomes less effective. As the disease progresses and neurons continue to be lost, these medications become less effective while at the same time they produce a complication marked by involuntary writhing movements. Diet and some forms of rehabilitation have shown some effectiveness at improving symptoms. Surgery to place microelectrodes for deep brain stimulation has been used to reduce motor symptoms in severe cases where drugs are ineffective. Evidence for treatments for the non-movement-related symptoms of PD, such as sleep disturbances and emotional problems, is less strong.

In 2015, PD affected 6.2 million people and resulted in about 117,400 deaths globally. Parkinson's disease typically occurs in people over the age of 60, of which about one percent are affected. Males are more often affected than females at a ratio of around 3:2. When it is seen in people before the age of 50, it is called young-onset PD. The average life expectancy following diagnosis is between 7 and 14 years. The disease is named after the English doctor James Parkinson, who published the first detailed description in An Essay on the Shaking Palsy, in 1817. Public awareness campaigns include World Parkinson's Day (on the birthday of James Parkinson, 11 April) and the use of a red tulip as the symbol of the disease. People with Parkinson's who have increased the public's awareness of the condition include actor Michael J. Fox, Olympic cyclist Davis Phinney, and late professional boxer Muhammad Ali.

Source: Wikipedia

There is no cure for Parkinson's disease.
To prevent Parkinson's disease, read a lot of books and join communities, to stimulate your brain. Besides, drink one cup of coffee each day, or two cups of green tea everyday to boost caffeine substance in the blood.

Brain consists of cells interconnected to each other. In reality, imagine a brain is like a city full of houses. One house is like one cell in the brain. Each house must have cables connected to the electricity poles, which will connect to the main power source. Then, you can have electricity at home.

Electricity in real life is like battery. You need to recharge that battery so it can function properly.


If you see the above brain picture, the lines represent your memory. When you access that memory often, the line is getting stronger, and you'll remember it more. When you don't access that memory, the line is getting weaker, and with time, you'll forget.

An example case, is when there's an exam tomorrow. You'll try to remember, memorise all your notes. That's when you create a line. That line is getting stronger and stronger when you finally remember the notes. After the exam, especially after you graduate, you rarely access that memory, the lines are getting weaker, and you lose some or all of your memorisation you learnt at school.

If you read books, socialise more, your brain will maintain the memory lines of common words, your family names, including reflex on how to perform daily activities. The chance of survival may increase.

Research shows that the blood of a person with Parkinson disease is missing caffeine. It's still early to say that caffeine (cigarette, tea, coffee, etc) can cure Parkinson, so it's best to limit to one to two cups each day.

Caffeine is a type of drug.
It can also result to addiction.
I'd refrain from any addiction.



Stay Fit with Information About How to Prevent Parkinson's Disease

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